Post dural puncture headache (PDPH)

As an anesthesiologist, it’s essential to delve into the intricacies of post dural puncture headache (PDPH), also referred to as post lumbar puncture headache. This common complication arises following diagnostic lumbar punctures, spinal anesthesia, and unintended dural punctures during epidural catheter placements. PDPH is characterized by its distinctive positional nature – intensifying in an upright … Read more

Serum Albumin and Serum Calcium: Interplay and Clinical Significance in Anesthesia and Immediate Postoperative Care

Serum albumin and serum calcium are two vital biochemical parameters regularly assessed in anesthesia and immediate postoperative care. Understanding their interaction and how changes in one affect the other is crucial for optimizing patient management during and after surgery. Serum Albumin: Serum albumin is a protein synthesized by the liver and constitutes a major portion … Read more

Unlocking the Neuroprotective Secrets of Volatile Anesthetics: Mechanisms and Implications

1. Introduction: Volatile anesthetics, including cyclopropane, have been studied for their neuroprotective properties. Initially, it was believed that these effects were primarily due to the suppression of cerebral metabolism. Recent research indicates that other protective factors, including interactions with receptors and channels, are involved. 2. Neuroprotective Impact During Ischemia: Research has primarily involved animal experiments … Read more

Exploring the Neuroprotective Potential of Intravenous Anesthetics in Cerebral Ischemia

Cerebral ischemia is a critical medical condition characterized by insufficient blood flow to the brain, which can have devastating consequences. Protecting and salvaging cerebral neuronal function in the face of ischemic insults is a top priority in clinical practice. Intravenous anesthetics, traditionally known for their role in inducing general anesthesia, have garnered attention due to … Read more

INTRANASAL MIDAZOLAM

Intranasal Midazolam is a pharmaceutical formulation of the benzodiazepine medication Midazolam, designed for administration through the nasal route. It is primarily used in medical and clinical settings for its sedative and anxiolytic properties, particularly for situations where rapid and non-invasive sedation or seizure control is required. Here’s a comprehensive overview of intranasal Midazolam:1. Indications: Seizure … Read more

Midazolam in Anesthesia Practice: A Comprehensive Guide for Anesthesiologists

Introduction:Midazolam is a benzodiazepine that plays a pivotal role in anesthesia practice due to its potent sedative, anxiolytic, and amnestic properties. Understanding its mechanisms, clinical applications, and variations is vital for optimizing patient care and safety.Mechanism:Midazolam’s mechanism revolves around enhancing gamma-aminobutyric acid (GABA) activity within the central nervous system. While it doesn’t directly activate GABA … Read more

RAPID SEQUENCE INDUCTION AND INTUBATION

Introduction: History of RSI: RSI, or Rapid Sequence Intubation, is a technique developed to secure the airway quickly in situations where the risk of aspiration is high. The concept was introduced in the 1970s to address the potential for regurgitation and aspiration during intubation. RSI involves rapid administration of an induction agent followed by a … Read more

CANNABIS – ANESTHESIA CONSIDERATION

This document provides a detailed elaboration of the potential adverse effects of cannabis smoking in the context of anesthetic care for anesthesiologists. 1. Pulmonary Effects: Smoking synthetic tetrahydrocannabinol (THC) products or cannabis can lead to airway irritation and exacerbation of underlying respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), and pneumonia. Similar to … Read more

PERIOPERATIVE MEDICINE MANAGEMENT

The management of chronic medications in the perioperative period involves several principles to ensure patient safety and optimal outcomes: Obtain a complete medication history and verify accuracy: All clinicians involved in patient care, including surgeons, anesthesiologists, and medical consultants, should review the patient’s medication history. This includes prescription drugs, over-the-counter medications, herbal supplements, and substances … Read more

Perioperative neurocognitive disorder (PND)

Perioperative neurocognitive disorder (PND) is a comprehensive term utilized to encompass alterations in behavior, mood, and cognition that may arise following surgery and anesthesia. This definition is in accordance with the criteria outlined in the Diagnostic and Statistical Manual 5th edition (DSM-V) for neurocognitive disorder (NCD). PND encompasses several distinct conditions, namely preexisting cognitive impairment, … Read more